Anti-FKBP135抗体(ab14434)

概述

  • 产品名称Anti-FKBP135抗体
    参阅全部 FKBP135 一抗
  • 描述
    兔多克隆抗体to FKBP135
  • 特异性We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • 经测试应用适用于: IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide (Unfortunately the amino acid sequence is considered to be commercially sensitive). The peptide sequence is within the region between aa1175 and the C-terminus (aa1234) of human FKBP135 using the numbering given in TrEMBL entry Q9Y4D0 (GeneID 23307).

  • 阳性对照
    • HeLa cells.
  • 常规说明Centrifuge tube to remove product from lid.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Antibody was purified using an epitope specific to FKBP135 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
  • 应用说明IP: Use at a concentration of 1 - 4 mcg/ml.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase (By similarity). Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement.
    • 序列相似性Belongs to the FKBP-type PPIase family.
      Contains 1 PPIase FKBP-type domain.
    • 结构域The PPIase FKBP-type domain seems to be inactive both for FK506-binding and enzymatic activity.
      The central coiled-coil region is responsible for association with early endosomes.
    • 细胞定位Cytoplasm. Cell projection > axon. Early endosome. Present in axons and neuronal growth cones.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 133 kDa FK506-binding protein antibody
      • 133 kDa FKBP antibody
      • C430014M02Rik antibody
      • FK506 binding protein 135 antibody
      • FK506-binding protein 15 antibody
      • FKB15_HUMAN antibody
      • FKBO133 antibody
      • FKBP-133 antibody
      • FKBP-15 antibody
      • FKBP133 antibody
      • Fkbp15 antibody
      • KIAA0674 antibody
      • mKIAA0674 antibody
      • Peptidyl prolyl cis trans isomerase antibody
      • RIKEN cDNA C430014M02 gene antibody
      • RP23 64F17.7 antibody
      • WAFL antibody
      • WASP and FKBP-like antibody
      see all

    Anti-FKBP135 antibody 图像

    • Antibodies: ab14432ab14433 and ab14434 used at 2 mcg/mg extract for IP. FKBP135 in NE and immunoprecipitated FKBP135 were detected using ab14434 at 0.2 mcg/ml. Detection: Chemiluminescence with an exposure time of 10 minutes.

    Anti-FKBP135 antibody (ab14434)参考文献

    ab14434 has not yet been referenced specifically in any publications.

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    I am sorry if it was misleading but the image supplied with Anti-FKBP135 antibodies ab14432, ab14433 and ab14434 are the same. They illustrate the IP performed with ab14432,...

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