Anti-FKBP135抗体(ab14434)

概述

  • 产品名称
    Anti-FKBP135抗体
    参阅全部 FKBP135 一抗
  • 描述
    兔多克隆抗体to FKBP135
  • 特异性
    We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • 经测试应用
    适用于: IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide (Unfortunately the amino acid sequence is considered to be commercially sensitive). The peptide sequence is within the region between aa1175 and the C-terminus (aa1234) of human FKBP135 using the numbering given in TrEMBL entry Q9Y4D0 (GeneID 23307).

  • 阳性对照
    • HeLa cells.
  • 常规说明
    Centrifuge tube to remove product from lid.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Antibody was purified using an epitope specific to FKBP135 immobilized on solid support.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
  • 应用说明
    IP: Use at a concentration of 1 - 4 mcg/ml.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase (By similarity). Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement.
    • 序列相似性
      Belongs to the FKBP-type PPIase family.
      Contains 1 PPIase FKBP-type domain.
    • 结构域
      The PPIase FKBP-type domain seems to be inactive both for FK506-binding and enzymatic activity.
      The central coiled-coil region is responsible for association with early endosomes.
    • 细胞定位
      Cytoplasm. Cell projection > axon. Early endosome. Present in axons and neuronal growth cones.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 133 kDa FK506-binding protein antibody
      • 133 kDa FKBP antibody
      • C430014M02Rik antibody
      • FK506 binding protein 135 antibody
      • FK506-binding protein 15 antibody
      • FKB15_HUMAN antibody
      • FKBO133 antibody
      • FKBP-133 antibody
      • FKBP-15 antibody
      • FKBP133 antibody
      • Fkbp15 antibody
      • KIAA0674 antibody
      • mKIAA0674 antibody
      • Peptidyl prolyl cis trans isomerase antibody
      • RIKEN cDNA C430014M02 gene antibody
      • RP23 64F17.7 antibody
      • WAFL antibody
      • WASP and FKBP-like antibody
      see all

    图片

    • Antibodies: ab14432ab14433 and ab14434 used at 2 mcg/mg extract for IP. FKBP135 in NE and immunoprecipitated FKBP135 were detected using ab14434 at 0.2 mcg/ml. Detection: Chemiluminescence with an exposure time of 10 minutes.

    文献

    ab14434 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Thank you for contacting us and your interest in our products.


    I am sorry if it was misleading but the image supplied with Anti-FKBP135 antibodies ab14432, ab14433 and ab14434 are the same. They illustrate the IP performed with ab14432,...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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