The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 34 kDa.
Use at an assay dependent dilution.
功能May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
组织特异性Expressed by the liver and secreted in plasma.
序列相似性Belongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain.
结构域The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding.