Anti-Fibrinopeptide B抗体- C-terminal (ab86572)


  • 产品名称Anti-Fibrinopeptide B抗体- C-terminal
    参阅全部 Fibrinopeptide B 一抗
  • 描述
    兔多克隆抗体to Fibrinopeptide B - C-terminal
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide derived from the C-terminal region of Human Fibrinopeptide B, conjugated to KLH

  • 阳性对照
    • Mouse liver tissue lysate



Our Abpromise guarantee covers the use of ab86572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Predicted molecular weight: 56 kDa.
ELISA 1/1000.


  • 功能Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
  • 疾病相关Defects in FGB are a cause of thrombophilia.
    Defects in FGB are a cause of congenital afibrinogenemia (CAFBN) [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen.
  • 序列相似性Contains 1 fibrinogen C-terminal domain.
  • 结构域A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure.
  • 翻译后修饰Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epididymis secretory sperm binding protein Li 78p antibody
    • FGB antibody
    • FIBB_HUMAN antibody
    • Fibrinogen B beta polypeptide antibody
    • Fibrinogen beta chain antibody
    • Fibrinogen beta polypeptide chain antibody
    • Fibrinopeptide B antibody
    • HEL S 78p antibody
    • Liver regeneration-related protein LRRG036/LRRG043/LRRG189 antibody
    • MGC104327 antibody
    • MGC120405 antibody
    • OTTHUMP00000197066 antibody
    see all

Anti-Fibrinopeptide B antibody - C-terminal 图像

  • Anti-Fibrinopeptide B antibody - C-terminal (ab86572) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 56 kDa

Anti-Fibrinopeptide B antibody - C-terminal (ab86572)参考文献

ab86572 has not yet been referenced specifically in any publications.

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