Anti-FHIT (phospho Y114)抗体(ab111557)

概述

  • 产品名称Anti-FHIT (phospho Y114)抗体
    参阅全部 FHIT 一抗
  • 描述
    兔多克隆抗体to FHIT (phospho Y114)
  • 特异性ab111557 detects endogenous levels of FHIT only when phosphorylated at tyrosine 114.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from Human FHIT around the phosphorylation site of Tyrosine 114 (S-I-YP-E-E).

  • 阳性对照
    • Human colon carcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 49% PBS, 0.88% Sodium chloride
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111557 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性FHIT (fragile histidine triad) cleaves adenosine 5' PPP 5' A to yield AMP and ADP. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. FHIT physically associates with ubiquitin conjugating enzyme 9.
  • 细胞定位Cytoplasmic
  • 数据库链接
  • 别名
    • AP3A hydrolase antibody
    • AP3A hydrolase fragile site 3p14.2 antibody
    • AP3Aase antibody
    • Bis 5' adenosyl triphosphatase antibody
    • Bis(5' adenosyl) triphosphatase antibody
    • Diadenosine 5' 5''' P1 P3 triphosphate hydrolase antibody
    • Dinucleosidetriphosphatase antibody
    • FRA 3B antibody
    • FRA3B antibody
    • Fragile histidine triad antibody
    • Fragile histidine triad gene antibody
    • Fragile histidine triad protein antibody
    • Tumor suppressor protein antibody
    see all

Anti-FHIT (phospho Y114) antibody 图像

  • ab111557, at 1/50 dilution, staining FHIT in paraffin-embedded Human colon carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-FHIT (phospho Y114) antibody (ab111557)参考文献

ab111557 has not yet been referenced specifically in any publications.

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