Anti-FGF9抗体[FG9-77] (ab10424)

概述

  • 产品名称Anti-FGF9抗体[FG9-77]
    参阅全部 FGF9 一抗
  • 描述
    小鼠单克隆抗体[FG9-77] to FGF9
  • 特异性Monoclonal Anti-FGF9 reacts specifically with recombinant FGF9 (fibroblast growth factor 9). It does not cross-react with human FGF Acidic and FGF Basic.
  • 经测试应用适用于: ELISA, Dot blot, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant full length protein (Mouse).

性能

应用

Our Abpromise guarantee covers the use of ab10424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
Dot blot Use a concentration of 5 µg/ml.
WB Use at an assay dependent dilution. Detects a band of approximately 25 kDa.

靶标

  • 功能May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
  • 组织特异性Glial cells.
  • 疾病相关Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3) [MIM:612961]. Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness.
  • 序列相似性Belongs to the heparin-binding growth factors family.
  • 翻译后修饰Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step.
    N-glycosylated.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FGF 9 antibody
    • FGF-9 antibody
    • FGF9 antibody
    • FGF9_HUMAN antibody
    • Fibroblast growth factor 9 antibody
    • GAF antibody
    • Glia Activating Factor antibody
    • Glia-activating factor antibody
    • HBFG 9 antibody
    • HBFG9 antibody
    • HBGF-9 antibody
    • Heparin-binding growth factor 9 antibody
    • MGC119914 antibody
    • MGC119915 antibody
    • SYNS3 antibody
    see all

Anti-FGF9 antibody [FG9-77] (ab10424)参考文献

ab10424 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab10424.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"