概述

  • 产品名称Anti-FGF9抗体
    参阅全部 FGF9 一抗
  • 描述
    兔多克隆抗体to FGF9
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to an internal sequence of Human FGF9.

  • 阳性对照
    • Rat brain tissue; Rat brain tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab115821 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. Detection limit is 1ng/lane, under reducing and non-reducing conditions.
IHC-P Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
  • 组织特异性Glial cells.
  • 疾病相关Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3) [MIM:612961]. Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness.
  • 序列相似性Belongs to the heparin-binding growth factors family.
  • 翻译后修饰Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step.
    N-glycosylated.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FGF 9 antibody
    • FGF-9 antibody
    • FGF9 antibody
    • FGF9_HUMAN antibody
    • Fibroblast growth factor 9 antibody
    • GAF antibody
    • Glia Activating Factor antibody
    • Glia-activating factor antibody
    • HBFG 9 antibody
    • HBFG9 antibody
    • HBGF-9 antibody
    • Heparin-binding growth factor 9 antibody
    • MGC119914 antibody
    • MGC119915 antibody
    • SYNS3 antibody
    see all

Anti-FGF9 antibody 图像

  • Anti-FGF9 antibody (ab115821) at 1 µg/ml + Rat brain tissue lysate

    Predicted band size : 23 kDa
  • ab115821 at 1µg/ml staining FGF9 in by Paraffin-embedded Human Rat brain tissue by Immunohistochemistry.

Anti-FGF9 antibody (ab115821)参考文献

ab115821 has not yet been referenced specifically in any publications.

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