Anti-FGF21抗体(ab57059)

概述

  • 产品名称
  • 描述
    小鼠单克隆抗体to FGF21
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 30-210 of Human FGF21

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.

性能

应用

Our Abpromise guarantee covers the use of ab57059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

靶标

  • 功能
    Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
  • 序列相似性
    Belongs to the heparin-binding growth factors family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FGF 21 antibody
    • FGF-21 antibody
    • Fgf21 antibody
    • FGF21_HUMAN antibody
    • FGFL antibody
    • Fibroblast growth factor 21 antibody
    • PRO10196 antibody
    • UNQ3115 antibody
    see all

图片

  • Western blot against tagged recombinant protein immunogen using ab57059 FGF21 antibody at 1ug/ml. Predicted band size of immunogen is 46 kDa

实验方案

文献

ab57059 has not yet been referenced specifically in any publications.

客户评价及客户问答

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Western blot
Sample
Human Cell lysate - whole cell (Adipocytes)
Loading amount
8 µg
Specification
Adipocytes
Gel Running Conditions
Reduced Denaturing (15% gel)
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 24°C
Username

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Verified customer

提交于 Jun 10 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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