Anti-FGF1抗体(ab18963)

概述

性能

应用

Our Abpromise guarantee covers the use of ab18963 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 17 kDa.
ELISA Use a concentration of 2 - 3 µg/ml.
Neutralising Use a concentration of 3 - 6 µg/ml.

靶标

  • 功能The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
  • 序列相似性Belongs to the heparin-binding growth factors family.
  • 细胞定位Secreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acidic fibroblast growth factor antibody
    • aFGF antibody
    • Beta endothelial cell growth factor antibody
    • Beta-endothelial cell growth factor antibody
    • ECGF antibody
    • ECGF beta antibody
    • ECGF-beta antibody
    • ECGFA antibody
    • ECGFB antibody
    • Endothelial Cell Growth Factor alpha antibody
    • Endothelial Cell Growth Factor beta antibody
    • FGF 1 antibody
    • FGF alpha antibody
    • Fgf1 antibody
    • FGF1_HUMAN antibody
    • FGFA antibody
    • Fibroblast Growth Factor 1 Acidic antibody
    • Fibroblast growth factor 1 antibody
    • GLIO703 antibody
    • HBGF 1 antibody
    • HBGF-1 antibody
    • HBGF1 antibody
    • Heparin binding growth factor 1 antibody
    • Heparin binding growth factor 1 precursor antibody
    • Heparin-binding growth factor 1 antibody
    see all

Anti-FGF1 antibody 图像

  • Anti-FGF1 antibody (ab18963) at 1 µg/ml + Spinal Cord (Rat) Tissue Lysate at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Predicted band size : 17 kDa
    Observed band size : 17 kDa
    Additional bands at : 20 kDa (possible post-translational modification).

Anti-FGF1 antibody (ab18963)参考文献

ab18963 has not yet been referenced specifically in any publications.

Product Wall

I now have a bit more information to share with you. As discussed, Anti-FGF1 (ab58311) is raised against a fusion protein of FGF1 (with a well know purification tag) of ~45 kDa, and it is this fusion protein which has been expressed and detected in the...

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