概述

  • 产品名称
  • 描述
    山羊多克隆抗体to Fetuin
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment (alpha 2-HS glycoprotein) processed to remove a 40 amino acid residue bridging peptide resulting in the mature form of the protein (Human).

  • 阳性对照
    • WB: Human serum or purified Fetuin.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.01% Sodium Azide
    Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate. pH 7.2
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 纯化说明
    Ab34505 was purified from monospecific antiserum by a multistep process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab34505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明
    ELISA: 1/40,000 - 1/200,000.
    WB: 1/10000 - 1/20000. Detects a band of approximately 58 kDa.

    Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
    • 组织特异性
      Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
    • 序列相似性
      Belongs to the fetuin family.
      Contains 2 cystatin fetuin-A-type domains.
    • 翻译后修饰
      Phosphorylation sites are present in the extracelllular medium.
      O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4; N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 16G2 antibody
      • A2HS antibody
      • AHS antibody
      • Ahsg antibody
      • Alpha 2 HS glycoprotein antibody
      • Alpha 2 Z globulin antibody
      • Alpha 2HS glycoprotein antibody
      • Alpha-2-HS-glycoprotein chain B antibody
      • Alpha-2-Z-globulin antibody
      • Ba alpha 2 glycoprotein antibody
      • Ba-alpha-2-glycoprotein antibody
      • FETUA antibody
      • FETUA_HUMAN antibody
      • FETUB antibody
      • Fetuin A antibody
      • Fetuin B antibody
      • Fetuin like protein antibody
      • Fetuin-A antibody
      • FetuinA antibody
      • FetuinB antibody
      • Gugu antibody
      • HSGA antibody
      • IRL 685 antibody
      • IRL685 antibody
      • PRO2743 antibody
      see all

    图片

    实验方案

    文献

    This product has been referenced in:
    • Kutikhin AG  et al. Apoptosis-mediated endothelial toxicity but not direct calcification or functional changes in anti-calcification proteins defines pathogenic effects of calcium phosphate bions. Sci Rep 6:27255 (2016). WB . Read more (PubMed: 27251104) »

    See 1 Publication for this product

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    There are currently no Customer reviews or Questions for ab34505.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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