Anti-Ferritin抗体(Biotin) (ab7333)

概述

• 产品名称Anti-Ferritin抗体(Biotin)
  参阅全部 Ferritin 一抗
• 描述
  兔多克隆抗体to Ferritin (Biotin)
• 偶联物Biotin
• 经测试应用适用于: ELISA, IHC-Fr, WBmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  Full length native protein (purified) corresponding to Human Ferritin. From human spleen
  Database link: P02794

• 常规说明

  Biotinamidocaproate N-Hydroxysuccinimide Ester (BAC) Biotin/Protein Ratio: 10-20 BAC molecules per rabbit IgG molecule.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• 存储溶液pH: 7.60
  Preservative: 0.01% Sodium azide
  Constituents: 0.88% Sodium chloride, 1% BSA, 0.42% Potassium phosphate
• Concentration information loading...
• 纯度IgG fraction
• 纯化说明This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer.
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Alzheimer's disease
  • Other

  • Cardiovascular
  • Blood
  • Serum Proteins

  • Signal Transduction
  • Metabolism
  • Mitochondrial

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Types of disease
  • Neurodegenerative disease

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
• 序列相似性Belongs to the ferritin family.
  Contains 1 ferritin-like diiron domain.

• Target information above from: UniProt accession P02794 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 2495 Human
  • Entrez Gene: 2512 Human
  • Omim: 608847 Human
  • SwissProt: P02792 Human
  • SwissProt: P02794 Human
  • Unigene: 524910 Human
  • Unigene: 645560 Human
• 形式Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
• 别名
  • Cell proliferation-inducing gene 15 protein antibody
  • Ferritin H subunit antibody
  • Ferritin heavy chain antibody

  • Ferritin heavy polypeptide 1 antibody
  • Ferritin L subunit antibody
  • Ferritin light polypeptide antibody
  • Ferritin, heavy polypeptide antibody
  • FRIH_HUMAN antibody
  • FTH antibody
  • FTH1 antibody
  • FTL antibody

  see all