Anti-FER (phospho Y402)抗体(ab79573)
Key features and details
- Rabbit polyclonal to FER (phospho Y402)
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FER (phospho Y402)抗体
参阅全部 FER 一抗 -
描述
兔多克隆抗体to FER (phospho Y402) -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Synthetic peptide corresponding to Human FER (phospho Y402).
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阳性对照
- Human brain tissue; Jurkat cell extracts starved for 24 hours.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab79573 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab79573于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 93 kDa.
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IHC-P |
1/50 - 1/100.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 93 kDa. |
IHC-P
1/50 - 1/100. |
靶标
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功能
Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control. -
组织特异性
Expressed in a variety of lymphoid cell lines. -
序列相似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
Contains 1 FCH domain.
Contains 1 protein kinase domain.
Contains 1 SH2 domain. -
细胞定位
Cytoplasm. Nucleus. Associated with the chromatin. - Information by UniProt
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数据库链接
- Entrez Gene: 2241 Human
- Entrez Gene: 14158 Mouse
- Omim: 176942 Human
- SwissProt: P16591 Human
- SwissProt: P70451 Mouse
- Unigene: 221472 Human
- Unigene: 23039 Mouse
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别名
- c FER antibody
- Feline encephalitis virus related kinase FER antibody
- Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94) antibody
see all
图片
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ab79573, at a 1/50 dilution, staining FER in paraffin embedded human brain tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunizing peptide.
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All lanes : Anti-FER (phospho Y402) antibody (ab79573) at 1/500 dilution
Lane 1 : Jurkat cell extracts, starved (24 hours)
Lane 2 : Jurkat cell extracts, starved (24 hours) with immunizing phospho peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 93 kDa
Observed band size: 93 kDa
Additional bands at: 50 kDa. We are unsure as to the identity of these extra bands.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab79573 被引用在 2 文献中.
- Amtul Z et al. Comorbid rat model of ischemia and β-amyloid toxicity: striatal and cortical degeneration. Brain Pathol 25:24-32 (2015). PubMed: 24725245
- Chang SF et al. Different modes of endothelial-smooth muscle cell interaction elicit differential ß-catenin phosphorylations and endothelial functions. Proc Natl Acad Sci U S A 111:1855-60 (2014). PubMed: 24449884