The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit (By similarity). May participate in antiinflammatory signaling via its interaction with PTGER4.
组织特异性Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).
通路Protein modification; protein ubiquitination.
序列相似性Belongs to the fem-1 family. Contains 9 ANK repeats. Contains 2 TPR repeats.