RabMAb

Anti-FDPS抗体[EPR4628] (ab109007)

概述

  • 产品名称Anti-FDPS抗体[EPR4628]
    参阅全部 FDPS 一抗
  • 描述
    兔单克隆抗体[EPR4628] to FDPS
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
    不适用于: ICC or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues near the C-terminus of Human FDPS.

  • 阳性对照
    • THP1, HepG2, and Human fetal liver lysates; Human kidney tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab109007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Heat up to 98 degrees C, below boiling, and then let cool for 10-20 min.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC or IP.
  • 靶标

    • 功能Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
    • 通路Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
      Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
    • 序列相似性Belongs to the FPP/GGPP synthase family.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • (2E antibody
      • (2E,6E) farnesyl diphosphate synthase antibody
      • 6E)-farnesyl diphosphate synthase antibody
      • Dimethylallyltranstransferase antibody
      • Farnesyl diphosphate synthase antibody
      • Farnesyl diphosphate synthetase antibody
      • Farnesyl pyrophosphate synthase antibody
      • Farnesyl pyrophosphate synthetase antibody
      • Fdps antibody
      • FPP synthase antibody
      • FPP synthetase antibody
      • FPPS antibody
      • FPPS_HUMAN antibody
      • FPS antibody
      • Geranyltranstransferase antibody
      see all

    Anti-FDPS antibody [EPR4628] 图像

    • All lanes : Anti-FDPS antibody [EPR4628] (ab109007) at 1/1000 dilution

      Lane 1 : THP1 cell lysates
      Lane 2 : HepG2 cell lysates
      Lane 3 : Human fetal liver lysates


      Predicted band size : 48 kDa
    • ab109007 at 1/100 dilution staining FDPS in Human kidney by Immunohistochemistry, Paraffin-embedded tissue.

    Anti-FDPS antibody [EPR4628] (ab109007)参考文献

    ab109007 has not yet been referenced specifically in any publications.

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