The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 41 kDa).
相关性FCRLM1 belongs to a family of receptors for the Fc fragment of IgG, or FCGRs which are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLM1 may be involved in B-cell differentiation and lymphomagenesis.