RabMAb

Anti-FCGR1A抗体[EPR4623] (ab109449)

概述

  • 产品名称Anti-FCGR1A抗体[EPR4623]
    参阅全部 FCGR1A 一抗
  • 描述
    兔单克隆抗体[EPR4623] to FCGR1A
  • 经测试应用适用于: WB, IP, Flow Cytmore details
    不适用于: IHC-P
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in the extracellular domain of Human FCGR1A.

  • 阳性对照
    • U937, THP1, and HL60 cell lysates; U937 cells.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab109449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 64-78 kDa (predicted molecular weight: 43 kDa).
IP 1/10 - 1/100.
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for IHC-P.
  • 靶标

    • 功能High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
    • 组织特异性Monocyte/macrophage specific.
    • 序列相似性Belongs to the immunoglobulin superfamily. FCGR1 family.
      Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    • 翻译后修饰Phosphorylated on serine residues.
    • 细胞定位Cell membrane. Stabilized at the cell membrane through interaction with FCER1G.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD64 antibody
      • CD64A antibody
      • Fc fragment of IgG high affinity Ia receptor (CD64) antibody
      • Fc fragment of IgG, high affinity Ia, receptor for antibody
      • Fc gamma receptor antibody
      • Fc gamma receptor I A1 antibody
      • Fc gamma RI antibody
      • Fc gamma RIA antibody
      • Fc-gamma RI antibody
      • Fc-gamma RIA antibody
      • FCG1 antibody
      • FcgammaRIa antibody
      • FCGR1 antibody
      • FCGR1_HUMAN antibody
      • FCGR1A antibody
      • FcRI antibody
      • FLJ18345 antibody
      • High affinity immunoglobulin gamma Fc receptor I antibody
      • IGFR1 antibody
      • IgG Fc receptor I antibody
      • Immunoglobulin G Fc receptor I antibody
      • OTTHUMP00000013913 antibody
      see all

    Anti-FCGR1A antibody [EPR4623] 图像

    • All lanes : Anti-FCGR1A antibody [EPR4623] (ab109449) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : THP1 cell lysate
      Lane 3 : HL60 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 43 kDa
      Observed band size : 64-78 kDa (why is the actual band size different from the predicted?)
    • ab109449 at 1/100 dilution staining FCGR1A in U937 cells by Flow cytometry (shown in red). Rabbit IgG negative control (shown in green).
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-FCGR1A antibody [EPR4623] (ab109449)参考文献

    ab109449 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"