概述

  • 产品名称Anti-FBXO25抗体
    参阅全部 FBXO25 一抗
  • 描述
    小鼠单克隆抗体to FBXO25
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-368 of Human FBXO25

性能

应用

Our Abpromise guarantee covers the use of ab57051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT).
    • 组织特异性Expressed in all brain tissue observed.
    • 通路Protein modification; protein ubiquitination.
    • 疾病相关Note=A chromosomal aberration involving FBXO25 is a cause of X-linked mental retardation (XLMR). Translocation t(X;8)(p11.22;p23.3) with SHROOM4.
    • 序列相似性Contains 1 F-box domain.
    • 结构域The F-box is necessary for the interaction with SKP1.
    • 细胞定位Nucleus. In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1.
    • Information by UniProt
    • 数据库链接
    • 别名
      • F box only protein 25 antibody
      • F box protein 25 antibody
      • F box protein Fbx25 antibody
      • F-box only protein 25 antibody
      • FBX25 antibody
      • FBX25_HUMAN antibody
      • FBXO25 antibody
      • MGC20256 antibody
      • MGC51975 antibody
      • OTTHUMP00000115399 antibody
      see all

    Anti-FBXO25 antibody 图像



    • Predicted band size : 43 kDa
      FBXO25 antibody (ab57051) at 1ug/lane + COLO cell lysate at 25ug/lane.

    Anti-FBXO25 antibody (ab57051)参考文献

    ab57051 has not yet been referenced specifically in any publications.

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