参阅全部 FBXO25 一抗
Recombinant full length protein, corresponding to amino acids 1-368 of Human FBXO25
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: None
PBS, pH 7.2
Concentration information loading...
- 纯度Protein G purified
应用说明WB: Use at a concentration of 1-5 µg/ml.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- 功能Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT).
- 组织特异性Expressed in all brain tissue observed.
- 通路Protein modification; protein ubiquitination.
- 疾病相关Note=A chromosomal aberration involving FBXO25 is a cause of X-linked mental retardation (XLMR). Translocation t(X;8)(p11.22;p23.3) with SHROOM4.
- 序列相似性Contains 1 F-box domain.
- 结构域The F-box is necessary for the interaction with SKP1.
- 细胞定位Nucleus. In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1.
Information by UniProt
- F box only protein 25 antibody
- F box protein 25 antibody
- F box protein Fbx25 antibody
Anti-FBXO25 antibody (ab57051)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"