概述

  • 产品名称Anti-FBXO2抗体
    参阅全部 FBXO2 一抗
  • 描述
    兔多克隆抗体to FBXO2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 234-296 of Human FBXO2 (NP_036300)

  • 阳性对照
    • A431, HepG2 cell lysate and H1299 whole cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab96391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.

靶标

  • 功能Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 F-box domain.
    Contains 1 FBA (F-box associated) domain.
  • 细胞定位Cytoplasm. Microsome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • F box gene 1 antibody
    • F box only protein 2 antibody
    • F box protein 2 antibody
    • F box protein only 2 antibody
    • F-box only protein 2 antibody
    • FBG 1 antibody
    • FBG1 antibody
    • Fbs 1 antibody
    • Fbs1 antibody
    • Fbs2 antibody
    • FBX 2 antibody
    • FBX2 antibody
    • FBX2_HUMAN antibody
    • FBXO 2 antibody
    • FBXO2 antibody
    • Neural F box protein NFB42 antibody
    • Neural F-box protein, 42-KD, rat, homolog of antibody
    • NFB 42 antibody
    • NFB42 antibody
    • OCP1 antibody
    • organ of Corti protein 1 antibody
    • Prpl4 antibody
    see all

Anti-FBXO2 antibody 图像

  • Anti-FBXO2 antibody (ab96391) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 33 kDa

Anti-FBXO2 antibody (ab96391)参考文献

ab96391 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96391.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"