概述

  • 产品名称Anti-FBXL3抗体
    参阅全部 FBXL3 一抗
  • 描述
    山羊多克隆抗体to FBXL3
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide:

    KRGGRDSDRNSSEE-C

    , corresponding to N terminal amino acids 2-15 of Human FBXL3.

  • 阳性对照
    • Human thyroid tissue; Human adipose lysate

性能

应用

Our Abpromise guarantee covers the use of ab115515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 49 kDa.
ELISA 1/32000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • 组织特异性Widely expressed.
  • 序列相似性Contains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • 细胞定位Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • 数据库链接
  • 别名
    • F box and leucine rich repeat protein 3 antibody
    • F box and leucine rich repeat protein 3A antibody
    • F box protein Fbl3a antibody
    • F-box and leucine-rich repeat protein 3A antibody
    • F-box/LRR-repeat protein 3 antibody
    • F-box/LRR-repeat protein 3A antibody
    • FBL3 antibody
    • FBL3A antibody
    • Fbxl3 antibody
    • FBXL3_HUMAN antibody
    • FBXL3A antibody
    see all

Anti-FBXL3 antibody 图像

  • ab115515, at 5µg/ml staining FBXL3 in formalin-fixed, paraffin-embedded Human thyroid tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-FBXL3 antibody (ab115515) at 1 µg/ml + Human adipose lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 49 kDa

Anti-FBXL3 antibody (ab115515)参考文献

ab115515 has not yet been referenced specifically in any publications.

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