Anti-Fascin抗体[EPR2681] (ab108607)


  • 产品名称Anti-Fascin抗体[EPR2681]
    参阅全部 Fascin 一抗
  • 描述
    兔单克隆抗体[EPR2681] to Fascin
  • 经测试应用适用于: WB, Flow Cytmore details
    不适用于: ICC,IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to internal sequence amino acids 435-460 of Human Fascin

  • 阳性对照
    • HeLa, SH-SY5Y and K-562 cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab108607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 55 kDa.
Flow Cyt 1/500 - 1/1000. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC,IHC-P or IP.
  • 靶标

    • 功能Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
    • 组织特异性Ubiquitous.
    • 序列相似性Belongs to the fascin family.
    • 结构域Composed of four beta-trefoil domains.
    • 翻译后修饰Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.
    • 细胞定位Cytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 55 kDa actin bundling protein antibody
      • 55 kDa actin-bundling protein antibody
      • Actin bundling protein antibody
      • actin bundling protein, 55-KD antibody
      • FAN 1 antibody
      • FAN1 antibody
      • Fascin 1 antibody
      • Fascin actin bundling protein 1 antibody
      • Fascin antibody
      • Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus) antibody
      • Fascin homolog 1 antibody
      • Fascin, sea urchin, homolog of, 1 antibody
      • Fascin1 antibody
      • FLJ38511 antibody
      • FSCN 1 antibody
      • FSCN1 antibody
      • FSCN1_HUMAN antibody
      • HSN antibody
      • p55 antibody
      • Singed (Drosophila) like (sea urchin fascin homolog like) antibody
      • Singed drosophila homolog like antibody
      • Singed like (fascin homolog sea urchin) (Drosophila) antibody
      • Singed like (fascin homolog sea urchin) antibody
      • Singed like protein antibody
      • Singed, drosophila, homolog of antibody
      • Singed-like protein antibody
      • SNL antibody
      • Strongylocentrotus purpuratus antibody
      see all

    Anti-Fascin antibody [EPR2681] 图像

    • All lanes : Anti-Fascin antibody [EPR2681] (ab108607) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 55 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-Fascin antibody [EPR2681] (ab108607)参考文献

    ab108607 has not yet been referenced specifically in any publications.

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