概述

  • 产品名称Anti-Fascin 2抗体
    参阅全部 Fascin 2 一抗
  • 描述
    兔多克隆抗体to Fascin 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 235-284 (AGTLKAGRNT RPGKDELFDL EESHPQVVLV AANHRYVSVR QGVNVSANQD) of Human Fascin 2 (NP_001070650).

  • 阳性对照
    • Human fetal brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab111601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
  • 组织特异性Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.
  • 疾病相关Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.
  • 序列相似性Belongs to the fascin family.
  • 细胞定位Cytoplasm > cytoskeleton. Cell projection > stereocilium.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Fascin homolog 2, actin bundling protein, retinal Strongylocentrotus purpuratus antibody
    • Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein, retinal antibody
    • Fascin-2 antibody
    • FSCN2 antibody
    • FSCN2_HUMAN antibody
    • Retinal fascin antibody
    • RFSN antibody
    • RP30 antibody
    see all

Anti-Fascin 2 antibody 图像

  • Anti-Fascin 2 antibody (ab111601) at 0.25 µg/ml + Human fetal brain lysate at 10 µg

    Predicted band size : 57 kDa

Anti-Fascin 2 antibody (ab111601)参考文献

ab111601 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111601.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"