Anti-Fas Ligand抗体[MFL3] (Phycoerythrin) (ab93566)

概述

  • 产品名称Anti-Fas Ligand抗体[MFL3] (Phycoerythrin)
    参阅全部 Fas Ligand 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[MFL3] to Fas Ligand (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    B6 mouse FasL cDNA-transfected baby hamster kidney (B6 FasL/BHK) cells.

  • 阳性对照
    • Mouse Fas Ligand transfected cells and activated T cells

性能

应用

Our Abpromise guarantee covers the use of ab93566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 0.5 - 1µg for 105 - 108 cells in a final volume of 100µL.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
    • 疾病相关Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.
    • 序列相似性Belongs to the tumor necrosis factor family.
    • 翻译后修饰N-glycosylated.
      The soluble form derives from the membrane form by proteolytic processing.
    • 细胞定位Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ALPS1B antibody
      • Apoptosis (APO 1) antigen ligand 1 antibody
      • Apoptosis antigen ligand 1 antibody
      • Apoptosis antigen ligand antibody
      • APT1LG1 antibody
      • APTL antibody
      • CD178 antibody
      • CD178 antigen antibody
      • CD95 ligand antibody
      • CD95-L antibody
      • CD95L antibody
      • CD95L protein antibody
      • Fas antigen ligand antibody
      • Fas L antibody
      • Fas ligand (TNF superfamily member 6) antibody
      • Fas ligand antibody
      • FASL antibody
      • Fasl Fas ligand (TNF superfamily member 6) antibody
      • FASLG antibody
      • Generalized lymphoproliferative disease antibody
      • Gld antibody
      • soluble form antibody
      • TNFL6_HUMAN antibody
      • TNFSF6 antibody
      • Tumor necrosis factor (ligand) superfamily member 6 antibody
      • Tumor necrosis factor ligand superfamily member 6 antibody
      see all

    Anti-Fas Ligand antibody [MFL3] (Phycoerythrin) 图像

    • Surface staining of mouse Fas Ligand transfected cells with 0.5µg ab93566. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

    Anti-Fas Ligand antibody [MFL3] (Phycoerythrin) (ab93566)参考文献

    ab93566 has not yet been referenced specifically in any publications.

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