PE Anti-Fas Ligand抗体[MFL3] (ab93566)
Key features and details
- PE Armenian hamster monoclonal [MFL3] to Fas Ligand
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG
Related conjugates and formulations
概述
-
产品名称
PE Anti-Fas Ligand抗体[MFL3]
参阅全部 Fas Ligand 一抗 -
描述
PE亚美尼亚仓鼠单克隆抗体[MFL3] to Fas Ligand -
宿主
Armenian hamster -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse Fas Ligand. C57BL/6 Mouse Fas cDNA transfected newborn Syrian Hamster kidney (BHK) cells
Database link: P41047 -
阳性对照
- Mouse Fas Ligand transfected cells and activated T cells.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
-
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
MFL3 -
同种型
IgG -
研究领域
相关产品
-
Alternative Versions
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab93566于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
说明 |
---|
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
-
功能
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. -
疾病相关
Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly. -
序列相似性
Belongs to the tumor necrosis factor family. -
翻译后修饰
N-glycosylated.
The soluble form derives from the membrane form by proteolytic processing. -
细胞定位
Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface. - Information by UniProt
-
数据库链接
- Entrez Gene: 14103 Mouse
- SwissProt: P41047 Mouse
- Unigene: 3355 Mouse
-
别名
- ALPS1B antibody
- Apoptosis (APO 1) antigen ligand 1 antibody
- Apoptosis antigen ligand 1 antibody
see all
图片
数据表及文件
-
Datasheet download
文献 (0)
ab93566 尚未被引用在任何文献中。