概述

  • 产品名称Anti-FANCG抗体
    参阅全部 FANCG 一抗
  • 描述
    山羊多克隆抗体to FANCG
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog, Pig, Chimpanzee, Macaque Monkey
  • 免疫原

    Synthetic peptide:

    LEEFRTSLPKSCDL

    , corresponding to C terminal amino acids 609-622 of Human FANCG

  • 阳性对照
    • HeLa cell lysate, Jurkat cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/32000.
    WB: Use at a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
    • 组织特异性Highly expressed in testis and thymus. Found in lymphoblasts.
    • 疾病相关Defects in FANCG are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
    • 序列相似性Contains 4 TPR repeats.
    • 细胞定位Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DNA repair protein XRCC9 antibody
      • FAG antibody
      • FANCG antibody
      • FANCG_HUMAN antibody
      • Fanconi anaemia complementation group G antibody
      • Fanconi anemia group G protein antibody
      • Protein FACG antibody
      • X ray repair, complementing defective, in Chinese hamster cells 9 antibody
      • X-ray repair, complementing defective, in Chinese hamster, 9 antibody
      • XRCC9 antibody
      see all

    Anti-FANCG antibody 图像

    • Anti-FANCG antibody (ab77193) at 0.5 µg/ml + Jurkat nuclear lysate in RIPA buffer at 35 µg

      Predicted band size : 69 kDa
    • Anti-FANCG antibody (ab77193) at 0.5 µg/ml + HeLa cell lysate in RIPA buffer at 35 µg
      Developed using the ECL technique

      Predicted band size : 69 kDa
      Observed band size : 69 kDa


      Exposure time : 1 hour

    Anti-FANCG antibody (ab77193)参考文献

    ab77193 has not yet been referenced specifically in any publications.

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