Anti-FANCE抗体[2346C5a] (ab70600)

概述

  • 产品名称Anti-FANCE抗体[2346C5a]
    参阅全部 FANCE 一抗
  • 描述
    小鼠单克隆抗体[2346C5a] to FANCE
  • 经测试应用适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment of human FANCE derived from an internal sequence.

  • 阳性对照
    • Recombinant human FANCE.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4.
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab70600 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
  • 克隆单克隆
  • 克隆编号2346C5a
  • 同种型IgG2b
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab70600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Detects a band of approximately 37 kDa (predicted molecular weight: 59 kDa).
Dot blot Use at an assay dependent dilution.

靶标

  • 功能As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
  • 疾病相关Fanconi anemia complementation group E
  • 翻译后修饰Phosphorylated. Phosphorylation by CHEK1 at Thr-346 and Ser-374 regulates its function in DNA cross-links repair.
    Ubiquitinated. Phosphorylation by CHEK1 induces polyubiquitination and degradation.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2810451D06Rik antibody
    • AI415634 antibody
    • AW209126 antibody
    • FACE antibody
    • FAE antibody
    • FANCE antibody
    • FANCE_HUMAN antibody
    • Fanconi anemia complementation group E antibody
    • Fanconi anemia group E protein antibody
    • OTTHUMP00000016254 antibody
    • Protein FACE antibody
    • RGD1561045 antibody
    see all

Anti-FANCE antibody [2346C5a] 图像

Anti-FANCE antibody [2346C5a] (ab70600)参考文献

ab70600 has not yet been referenced specifically in any publications.

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