概述

  • 产品名称Anti-FAM83H抗体
    参阅全部 FAM83H 一抗
  • 描述
    兔多克隆抗体to FAM83H
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    antigen sequence: SDKDKCSAIF RSDSLGTQGR LSRTLPASAE ERDRLLRRME SMRKEKRVYS RFEVFCKKEE ASSPGAGEGP AEEGTRDSKV GKFVPKILGT F, corresponding to amino acids 1085-1175 of Human FAM83H.

  • 阳性对照
    • Human vagina tissue; RT-4 lysate and Human tonsil lysate

性能

应用

Our Abpromise guarantee covers the use of ab121816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 功能May play a major role in the structural organization and calcification of developing enamel.
  • 组织特异性Expressed in the tooth follicle.
  • 疾病相关Defects in FAM83H are the cause of amelogenesis imperfecta type 3 (AI3) [MIM:130900]. AI3 is an autosomal dominant hypomineralized form of amelogenesis imperfecta, a defect of enamel formation. AI3 is characterized by enamel of normal thickness, but soft and with cheesy consistency. Enamel is lost from tooth soon after eruption.
  • 序列相似性Belongs to the FAM83 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI3 antibody
    • FA83H_HUMAN antibody
    • Fam83h antibody
    • Family with sequence similarity 83 member H antibody
    • Protein FAM83H antibody
    see all

Anti-FAM83H antibody 图像

  • Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
    Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
  • ab121816, at 1/15 dilution, staining FAM83H in paraffin-embedded Human vagina tissue by Immunohistochemistry.
  • All lanes : Anti-FAM83H antibody (ab121816) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate
  • Immunohistochemical staining of Human vagina shows moderate cytoplasmic positivity in squamous epithelial cells using ab121816

Anti-FAM83H antibody (ab121816)参考文献

ab121816 has not yet been referenced specifically in any publications.

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