概述

  • 产品名称Anti-FAM161A抗体
    参阅全部 FAM161A 一抗
  • 描述
    兔多克隆抗体to FAM161A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 120-169 (RKEWVPTITV PEPFQMMIRE QKKKEESMKS KSDIEMVHKA LKKQEEDPEY) of Human FAM161A, isoform 2.

  • 阳性对照
    • Jurkat cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Constituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

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应用

Our Abpromise guarantee covers the use of ab115810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 65 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 组织特异性Isoform 1 and isoform 3 are widely expressed with highest levels in retina and testis, with isoform 1 being the mot abundant in all tissues tested.
  • 疾病相关Defects in FAM161A are the cause of retinitis pigmentosa type 28 (RP28) [MIM:606068]. A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • 序列相似性Belongs to the FAM161 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • F161A_HUMAN antibody
    • Fam161a antibody
    • Family with sequence similarity 161, member A antibody
    • FLJ13305 antibody
    • Hypothetical protein LOC84140 antibody
    • MGC129982 antibody
    • MGC129983 antibody
    • OTTHUMP00000201353 antibody
    • Protein FAM161A antibody
    see all

Anti-FAM161A antibody 图像

  • Anti-FAM161A antibody (ab115810) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 65 kDa

Anti-FAM161A antibody (ab115810)参考文献

This product has been referenced in:
  • Karlstetter M  et al. Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Hum Mol Genet N/A:N/A (2014). WB ; Mouse . Read more (PubMed: 24833722) »

See 1 Publication for this product

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