概述

描述

  • 性质Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab54083 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    Blocking - Blocking peptide for Anti-FADD antibody (ab24533)

  • 纯度> 90 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • FADD
    • FADD protein
    • FADD_HUMAN
    • Fas (TNFRSF6) associated via death domain
    • Fas associated via death domain
    • Fas associating death domain containing protein
    • Fas associating protein
    • Fas associating protein with death domain
    • Fas TNFRSF6 associated via death domain
    • FAS-associated death domain protein
    • FAS-associating death domain-containing protein
    • GIG 3
    • GIG3
    • Growth inhibiting gene 3 protein
    • Growth-inhibiting gene 3 protein
    • H sapiens mRNA for mediator of receptor induced toxicity
    • Mediator of receptor induced toxicity
    • MGC8528
    • MORT 1
    • MORT1
    • Protein FADD
    see all
  • 功能Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
  • 组织特异性Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
  • 序列相似性Contains 1 death domain.
    Contains 1 DED (death effector) domain.
  • 结构域Contains a death domain involved in the binding of the corresponding domain within Fas receptor.
  • Information by UniProt

FADD peptide (ab54083)参考文献

ab54083 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab54083.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"