Anti-Factor XIIIa抗体[AC-1A1], prediluted (ab15207)

概述

  • 产品名称Anti-Factor XIIIa抗体[AC-1A1], prediluted
    参阅全部 Factor XIIIa 一抗
  • 描述
    小鼠单克隆抗体[AC-1A1] to Factor XIIIa, prediluted
  • 特异性This antibody reacts with Factor XIII in both reduced and nonreduced forms. It does not react with human Factor XIII B chain or human Factor XII.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein to A subunit of coagulation Factor XIII(Human).

  • 阳性对照
    • Capillary hemangioma, dermatofibroma, and placenta tissue.

性能

应用

Our Abpromise guarantee covers the use of ab15207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use. Antigen retrieval is not essential but may optimise staining.

    Not tested in other applications.
  • 靶标

    • 功能Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
    • 疾病相关Defects in F13A1 are the cause of factor XIII subunit A deficiency (FA13AD) [MIM:613225]. FA13AD is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
    • 序列相似性Belongs to the transglutaminase superfamily. Transglutaminase family.
    • 翻译后修饰The activation peptide is released by thrombin.
    • 细胞定位Cytoplasm. Secreted. Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
    • Information by UniProt
    • 数据库链接
    • 别名
      • bA525O21.1 (coagulation factor XIII, A1 polypeptide) antibody
      • Coagulation factor XIII A chain antibody
      • Coagulation factor XIII A1 polypeptide antibody
      • Coagulation factor XIII A1 subunit antibody
      • Coagulation factor XIII, A polypeptide antibody
      • Coagulation factor XIIIa antibody
      • F13A antibody
      • F13A_HUMAN antibody
      • F13a1 antibody
      • Factor XIIIA antibody
      • Fibrin stabilizing factor, A subunit antibody
      • Fibrinoligase antibody
      • FSF, A subunit antibody
      • Protein glutamine gamma glutamyltransferase A chain antibody
      • Protein-glutamine gamma-glutamyltransferase A chain antibody
      • TGase antibody
      • Transglutaminase A chain antibody
      • Transglutaminase. plasma antibody
      see all

    Anti-Factor XIIIa antibody [AC-1A1], prediluted (ab15207)参考文献

    ab15207 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. The antibody is purified from mouse ascite.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"