Anti-Factor XIIIa抗体(ab88905)

概述

  • 产品名称Anti-Factor XIIIa抗体
    参阅全部 Factor XIIIa 一抗
  • 描述
    小鼠多克隆抗体to Factor XIIIa
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human Factor XIIIa (AAH27963.1)

  • 阳性对照
    • Human pancreas tissue lysate, Factor XIIIa transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab88905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 83 kDa.

靶标

  • 功能Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
  • 疾病相关Defects in F13A1 are the cause of factor XIII subunit A deficiency (FA13AD) [MIM:613225]. FA13AD is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
  • 序列相似性Belongs to the transglutaminase superfamily. Transglutaminase family.
  • 翻译后修饰The activation peptide is released by thrombin.
  • 细胞定位Cytoplasm. Secreted. Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA525O21.1 (coagulation factor XIII, A1 polypeptide) antibody
    • Coagulation factor XIII A chain antibody
    • Coagulation factor XIII A1 polypeptide antibody
    • Coagulation factor XIII A1 subunit antibody
    • Coagulation factor XIII, A polypeptide antibody
    • Coagulation factor XIIIa antibody
    • F13A antibody
    • F13A_HUMAN antibody
    • F13a1 antibody
    • Factor XIIIA antibody
    • Fibrin stabilizing factor, A subunit antibody
    • Fibrinoligase antibody
    • FSF, A subunit antibody
    • Protein glutamine gamma glutamyltransferase A chain antibody
    • Protein-glutamine gamma-glutamyltransferase A chain antibody
    • TGase antibody
    • Transglutaminase A chain antibody
    • Transglutaminase. plasma antibody
    see all

Anti-Factor XIIIa antibody 图像

  • Anti-Factor XIIIa antibody (ab88905) at 1/500 dilution + Human pancreas tissue lysate at 50 µg

    Predicted band size : 83 kDa
    Observed band size : 83 kDa
  • All lanes : Anti-Factor XIIIa antibody (ab88905) at 1/500 dilution

    Lane 1 : Factor XIIIa transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 83 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-Factor XIIIa antibody (ab88905)参考文献

ab88905 has not yet been referenced specifically in any publications.

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