Anti-Factor VIII + VIII A2domain抗体[012] (ab21210)

概述

  • 产品名称Anti-Factor VIII + VIII A2domain抗体[012]
    参阅全部 Factor VIII + VIII A2domain 一抗
  • 描述
    小鼠单克隆抗体[012] to Factor VIII + VIII A2domain
  • 特异性ab21210 binds both human factor VIII and human factor VIIIa in solid-phase ELISA and human factor VIII A2 domain in immunoblotting techniques.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Native Factor VIII A2 domain (purified) (Human).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Sodium Azide
    Constituents: 0.15M Sodium chloride, 10mM Sodium phosphate. pH 7.4
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明Gel filtration and ion exchange chromatography (SDS-PAGE).
  • 克隆单克隆
  • 克隆编号012
  • 骨髓瘤NS1
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab21210 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 27 kDa. Dilution optimised using Chromogenic detection.

靶标

  • 相关性Haemophilia A is an X-linked, recessive, bleeding disorder caused by a deficiency in the activity of coagulation factor VIII. Affected individuals develop a variable phenotype of haemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds. The disorder is caused by heterogeneous mutations in the factor VIII gene. Up to 30% of haemophilia A patients given therapeutic fVIII can make inhibitory antibodies, the majority of which are reactive with its C2 and A2 domains.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • AHF antibody
    • Antihemophilic factor antibody
    • Coagulation factor VIII antibody
    • F8 antibody
    • F8B antibody
    • F8C antibody
    • Factor VIII antibody
    • FVIII antibody
    • HEMA antibody
    see all

Anti-Factor VIII + VIII A2domain antibody [012] (ab21210)参考文献

ab21210 has not yet been referenced specifically in any publications.

Product Wall

I am very pleased to hear you would like to accept our offer and test ab21210 in porcine. This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for porcine testing and include this c...

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Thank you for your enquiry. I have enquired at the source of the product but unfortunately, it seems that we do not have any available information on the epitope sequence for both these antibodies. I am sorry I can't be of more assistance in thi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"