概述

  • 产品名称Anti-Factor D抗体
    参阅全部 Factor D 一抗
  • 描述
    兔多克隆抗体to Factor D
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 160-209 (GRRPDSLQHV LLPVLDRATC NRRTHHDGAI TERLMCAESN RRDSCKGDSG) of Human Factor D (NP_001919).

  • 阳性对照
    • Human Fetal Lung lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
  • 疾病相关Defects in CFD are the cause of complement factor D deficiency (CFD deficiency) [MIM:134350]. CFD deficiency predisposes to invasive meningococcal disease.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adipsin antibody
    • Adipsin/complement factor D antibody
    • Adn antibody
    • C3 convertase activator antibody
    • CFAD_HUMAN antibody
    • CFD antibody
    • Complement factor D antibody
    • complement factor D preproprotein antibody
    • D component of complement antibody
    • DF antibody
    • FactorD antibody
    • PFD antibody
    • Properdin factor D antibody
    see all

Anti-Factor D antibody 图像

  • Anti-Factor D antibody (ab111880) at 1 µg/ml + Human Fetal Lung Lysate at 10 µg

    Predicted band size : 27 kDa

Anti-Factor D antibody (ab111880)参考文献

ab111880 has not yet been referenced specifically in any publications.

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