Anti-FACL4抗体- Aminoterminal end (ab70937)


  • 产品名称Anti-FACL4抗体- Aminoterminal end
    参阅全部 FACL4 一抗
  • 描述
    兔多克隆抗体to FACL4 - Aminoterminal end
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the N-terminal region of human FACL4.

  • 阳性对照
    • Human hepatocarcinoma tissue and 293 cell lysate.



Our Abpromise guarantee covers the use of ab70937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明ELISA: 1/1000.
    IHC-P: 1/50 - 1/100.
    WB: 1/100 - 1/500. Detects bands of approximately 28, 30 and 65 kDa (predicted molecular weight: 79 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses arachidonate and eicosapentaenoate as substrates.
    • 疾病相关Defects in ACSL4 are the cause of mental retardation X-linked type 63 (MRX63) [MIM:300387]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
      Defects in ACSL4 are involved in Alport syndrome with mental retardation midface hypoplasia and elliptocytosis (ATS-MR) [MIM:300194]. A X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis.
    • 序列相似性Belongs to the ATP-dependent AMP-binding enzyme family.
    • 细胞定位Mitochondrion outer membrane. Peroxisome membrane. Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ACS 4 antibody
      • ACS4 antibody
      • ACSL 4 antibody
      • Acsl4 antibody
      • ACSL4_HUMAN antibody
      • acyl CoA synthetase 4 antibody
      • Acyl CoA synthetase long chain family member 4 antibody
      • FACL 4 antibody
      • FACL4 antibody
      • Fatty acid Coenzyme A ligase antibody
      • fatty acid Coenzyme A ligase long-chain 4 antibody
      • LACS 4 antibody
      • LACS4 antibody
      • Lignoceroyl CoA synthase antibody
      • Long chain 4 antibody
      • long chain acyl CoA synthetase 4 antibody
      • long chain fatty acid CoA ligase 4 antibody
      • long chain fatty acid Coenzyme A ligase 4 antibody
      • Long-chain acyl-CoA synthetase 4 antibody
      • Long-chain-fatty-acid--CoA ligase 4 antibody
      • MRX63 antibody
      • MRX68 antibody
      see all

    Anti-FACL4 antibody - Aminoterminal end 图像

    • Anti-FACL4 antibody - Aminoterminal end (ab70937) at 1/100 dilution + 293 cell lysate at 12.5 µg

      Predicted band size : 79 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 28 kDa,30 kDa. We are unsure as to the identity of these extra bands.
    • Formalin-fixed, paraffin-embedded human hepatocarcinoma tissue reacted with ab70937 at a 1:50 dilution, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

    Anti-FACL4 antibody - Aminoterminal end (ab70937)参考文献

    ab70937 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab70937.
    Please use the links above to contact us or submit feedback about this product.