概述

  • 产品名称Anti-EYS抗体
  • 描述
    小鼠单克隆抗体to EYS
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 309-408 of Human EYS with a proprietary tag (XP_498111).

  • 阳性对照
    • Recombinant Human EYS Protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab118104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 351 kDa. XP_498111
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

靶标

  • 功能Required to maintain the integrity of photoreceptor cells.
  • 组织特异性Present in retina.
  • 疾病相关Defects in EYS are the cause of retinitis pigmentosa type 25 (RP25) [MIM:602772]. RP leads to degeneration of retinal photoreceptor cells. Patients suffer from night blindness, beginning at approximately 25 years of age, and deterioration of visual acuity (central vision), beginning at approximately 30 years of age. By age 55 to 60 years, many affected subjects have no perception of light in either eye.
  • 序列相似性Belongs to the EYS family.
    Contains 27 EGF-like domains.
    Contains 5 laminin G-like domains.
  • 细胞定位Secreted. Localizes in the photoreceptor cell layer.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA166P24.2 antibody
    • bA307F22.3 antibody
    • bA74E24.1 antibody
    • C6orf178 antibody
    • C6orf179 antibody
    • C6orf180 antibody
    • dJ1018A4.2 antibody
    • dJ22I17.2 antibody
    • dJ303F19.1 antibody
    • EGF-like protein 10 antibody
    • EGF-like protein 11 antibody
    • EGF-like-domain, multiple 10 antibody
    • EGF-like-domain, multiple 11 antibody
    • EGFL10 antibody
    • EGFL11 antibody
    • Epidermal growth factor-like protein 10 antibody
    • Epidermal growth factor-like protein 11 antibody
    • Eyes shut homolog (Drosophila) antibody
    • EYS antibody
    • EYS_HUMAN antibody
    • KIAA0663 antibody
    • OTTHUMP00000016688 antibody
    • OTTHUMP00000179129 antibody
    • OTTHUMP00000213100 antibody
    • OTTHUMP00000217891 antibody
    • Protein eyes shut homolog antibody
    • Protein spacemaker homolog antibody
    • RP25 antibody
    • SPAM antibody
    see all

Anti-EYS antibody 图像

  • Anti-EYS antibody (ab118104) at 5 µg/ml + recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 351 kDa
  • ab118104 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged EYS is 0.3 ng/ml.

Anti-EYS antibody (ab118104)参考文献

ab118104 has not yet been referenced specifically in any publications.

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