概述

  • 产品名称Anti-EXOSC6抗体
    参阅全部 EXOSC6 一抗
  • 描述
    兔多克隆抗体to EXOSC6
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Zebrafish
  • 免疫原

    A region within synthetic peptide: LYAADEEEAP GTRDPTRLRP VYARAGLLSQ AKGSAYLEAG GTKVLCAVSG, corresponding to amino acids 19-68 of Human EXOSC6

  • 阳性对照
    • Jurkat cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab50910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/62500.

WB Use a concentration of 1 µg/ml. Predicted molecular weight: 28 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known; however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • EAP4 antibody
    • Exosome component 6 antibody
    • hMtr3 antibody
    • hMtr3p antibody
    • homolog of yeast mRNA transport regulator 3 antibody
    • Mtr3 (mRNA transport regulator 3)-homolog antibody
    • MTR3 antibody
    • Mtr3p antibody
    • p11 antibody
    see all

Anti-EXOSC6 antibody 图像

  • Lane 1 : Marker
    Lane 2 : Anti-EXOSC6 antibody (ab50910) at 1 µg/ml

    Lane 1 : As above
    Lane 2 : Jurkat cell lysate at 10 µg

    Secondary
    Lane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution


    Predicted band size : 28 kDa

Anti-EXOSC6 antibody (ab50910)参考文献

ab50910 has not yet been referenced specifically in any publications.

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