概述

  • 产品名称Anti-EVER2抗体
    参阅全部 EVER2 一抗
  • 描述
    兔多克隆抗体to EVER2
  • 特异性ab70002 does only recognize the larger isoform. It has no cross-reactivity to EVER1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    18 amino acid peptide from near the amino terminus of human EVER2 (GenBank accession no. AAM44454).

  • 阳性对照
    • Rat thymus tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab70002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 81 kDa).

靶标

  • 相关性Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least two isoforms of EVER2 are known to exist.
  • 细胞定位Endoplasmic reticulum membrane; Multi pass membrane protein.
  • 数据库链接
  • 别名
    • epidermodysplasia verruciformis 2 antibody
    • Epidermodysplasia verruciformis protein 2 antibody
    • EV2 antibody
    • EVIN2 antibody
    • FLJ40668 antibody
    • FLJ43684 antibody
    • MGC102701 antibody
    • MGC40121 antibody
    • TMC8 antibody
    • Transmembrane channel like protein 8 antibody
    see all

Anti-EVER2 antibody 图像

  • Lane 1 : Anti-EVER2 antibody (ab70002) at 1 µg/ml
    Lane 2 : Anti-EVER2 antibody (ab70002) at 2 µg/ml

    Lane 1 : rat thymus tissue lysate
    Lane 2 : rat thymus tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 81 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-EVER2 antibody (ab70002)参考文献

ab70002 has not yet been referenced specifically in any publications.

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