Anti-EVER2抗体(ab102583)

概述

  • 产品名称Anti-EVER2抗体
    参阅全部 EVER2 一抗
  • 描述
    兔多克隆抗体to EVER2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 143-192,

    PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVG

    , of Human TMC8 (NP_689681).

  • 阳性对照
    • 721B cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab102583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 82 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least two isoforms of EVER2 are known to exist.
  • 细胞定位Endoplasmic reticulum membrane; Multi pass membrane protein.
  • 数据库链接
  • 别名
    • epidermodysplasia verruciformis 2 antibody
    • Epidermodysplasia verruciformis protein 2 antibody
    • EV2 antibody
    • EVIN2 antibody
    • FLJ40668 antibody
    • FLJ43684 antibody
    • MGC102701 antibody
    • MGC40121 antibody
    • TMC8 antibody
    • Transmembrane channel like protein 8 antibody
    see all

Anti-EVER2 antibody 图像

  • Anti-EVER2 antibody (ab102583) at 1 µg/ml + 721B cell lysate at 10 µg

    Predicted band size : 82 kDa

Anti-EVER2 antibody (ab102583)参考文献

ab102583 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry.

Unfortunately, we are not able to release the immunogen sequence for ab67325 and ab69859 as it is proprietary information.

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With regards to the additional band seen on the WB for ab102583, here is...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"