概述

  • 产品名称Anti-EVA1抗体
    参阅全部 EVA1 一抗
  • 描述
    兔多克隆抗体to EVA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    synthetic peptide corresponding to a region within N terminal amino acids 35-84 (LEAVNGTDARLKCTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDP F) of Human EVA1 (NP_005788)

  • 阳性对照
    • OVCAR-3 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab98877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. EVA1 is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. EVA1 expression is elevated in some T-cell leukemias. There are two isoforms.
  • 细胞定位Cell Membrane; Single-pass type I membrane protein, cytoskeleton
  • 数据库链接
  • 别名
    • Epithelial V like antigen 1 antibody
    • EVA antibody
    • EVA1 antibody
    • MPZL2 antibody
    • MPZL2 myelin protein zero like 2 antibody
    • Myelin protein zero like 2 antibody
    • Myelin protein zero like protein 2 antibody
    see all

Anti-EVA1 antibody 图像

  • Anti-EVA1 antibody (ab98877) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

    Predicted band size : 24 kDa

Anti-EVA1 antibody (ab98877)参考文献

ab98877 has not yet been referenced specifically in any publications.

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