概述

  • 产品名称Anti-EVA1抗体
    参阅全部 EVA1 一抗
  • 描述
    小鼠多克隆抗体to EVA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length EVA1 protein (Human)

  • 阳性对照
    • EVA1 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab67581 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 26 kDa (predicted molecular weight: 24 kDa).

靶标

  • 相关性Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. EVA1 is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. EVA1 expression is elevated in some T-cell leukemias. There are two isoforms.
  • 细胞定位Cell Membrane; Single-pass type I membrane protein, cytoskeleton
  • 数据库链接
  • 别名
    • Epithelial V like antigen 1 antibody
    • EVA antibody
    • EVA1 antibody
    • MPZL2 antibody
    • MPZL2 myelin protein zero like 2 antibody
    • Myelin protein zero like 2 antibody
    • Myelin protein zero like protein 2 antibody
    see all

Anti-EVA1 antibody 图像

  • All lanes : Anti-EVA1 antibody (ab67581) at 1/500 dilution

    Lane 1 : EVA1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 24 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)

Anti-EVA1 antibody (ab67581)参考文献

ab67581 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab67581.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"