Anti-Estrogen Related Receptor gamma抗体(ab77690)

概述

  • 产品名称Anti-Estrogen Related Receptor gamma抗体
    参阅全部 Estrogen Related Receptor gamma 一抗
  • 描述
    山羊多克隆抗体to Estrogen Related Receptor gamma
  • 特异性ab77690 is expected to recognise the reported isoform NP_001429.2.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog, Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    CRMSNKDRHIDS

    , corresponding to internal sequence amino acids 22-33 of Human Estrogen Related Receptor gamma (NP_001429.2).

  • 阳性对照
    • Human Brain (Cerebellum) and Breast lysates.

性能

应用

Our Abpromise guarantee covers the use of ab77690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Antibody detection limit dilution 1/16000.
    WB: Use at a concentration of 0.2 - 0.6 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.
    • 组织特异性Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
    • 序列相似性Belongs to the nuclear hormone receptor family. NR3 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 发展阶段Expressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
    • 翻译后修饰Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
      Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp781L1617 antibody
      • ERR 3 antibody
      • ERR G2 antibody
      • ERR gamma 2 antibody
      • ERR gamma-2 antibody
      • ERR3 antibody
      • ERR3_HUMAN antibody
      • ERRG 2 antibody
      • ERRG2 antibody
      • ERRgamma antibody
      • ESRRG antibody
      • Estrogen receptor related protein 3 antibody
      • Estrogen receptor-related protein 3 antibody
      • Estrogen-related receptor gamma antibody
      • FLJ16023 antibody
      • KIAA0832 antibody
      • NR3B3 antibody
      • Nuclear receptor subfamily 3 group B member 3 antibody
      see all

    Anti-Estrogen Related Receptor gamma antibody 图像

    • Anti-Estrogen Related Receptor gamma antibody (ab77690) at 0.2 µg/ml + Human Breast lysate (in RIPA buffer) at 35 µg

      Predicted band size : 51 kDa
      Observed band size : 51 kDa

    Anti-Estrogen Related Receptor gamma antibody (ab77690)参考文献

    ab77690 has not yet been referenced specifically in any publications.

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