Anti-Estrogen Receptor抗体(ab53572)

概述

  • 产品名称Anti-Estrogen Receptor抗体
  • 描述
    羊多克隆抗体to Estrogen Receptor
  • 经测试应用适用于: ELISA, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding from the DNA binding domain of human Estrogen receptor, conjugated to KLH.

性能

应用

Our Abpromise guarantee covers the use of ab53572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.

靶标

  • 功能Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Can activate the transcriptional activity of TFF1.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR3 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • 翻译后修饰Phosphorylated by cyclin A/CDK2. Phosphorylation probably enhances transcriptional activity.
    Glycosylated; contains N-acetylglucosamine, probably O-linked.
    Ubiquitinated. Deubiquitinated by OTUB1.
    Dimethylated by PRMT1 at Arg-260. The methylation may favor cytoplasmic localization.
    Palmitoylated (isoform 3). Not biotinylated (isoform 3).
  • 细胞定位Nucleus. Cytoplasm. Cell membrane. A minor fraction is associated with the inner membrane and Nucleus. Cytoplasm. Cell membrane. Associated with the inner membrane via palmitoylation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Atherosclerosis, susceptibility to, included antibody
    • DKFZp686N23123 antibody
    • ER Alpha antibody
    • ER antibody
    • ER Beta antibody
    • ER-alpha antibody
    • ER[a] antibody
    • ER[b] antibody
    • Era antibody
    • ERalpha antibody
    • Erb antibody
    • Erb2 antibody
    • ERbeta antibody
    • ESR antibody
    • ESR BETA antibody
    • ESR1 antibody
    • ESR1_HUMAN antibody
    • ESR2 antibody
    • ESRA antibody
    • ESRB antibody
    • Estr antibody
    • Estra antibody
    • Estradiol Receptor alpha antibody
    • Estradiol receptor antibody
    • Estradiol Receptor beta antibody
    • ESTRB antibody
    • Estrogen receptor 1 (alpha) antibody
    • Estrogen Receptor 1 antibody
    • Estrogen receptor 2 (ER beta) antibody
    • Estrogen Receptor 2 antibody
    • Estrogen receptor 2 ER beta antibody
    • Estrogen receptor alpha antibody
    • Estrogen receptor antibody
    • Estrogen receptor beta 4 antibody
    • Estrogen resistance, included antibody
    • HDL cholesterol, augmented response of, to hormone replacement, included antibody
    • Myocardial infarction, susceptibility to, included antibody
    • NR3A1 antibody
    • NR3A2 antibody
    • Nuclear receptor subfamily 3 group A member 1 antibody
    • Nuclear receptor subfamily 3 group A member 2 antibody
    • OTTHUMP00000017718 antibody
    • OTTHUMP00000017719 antibody
    • RNESTROR antibody
    see all

Anti-Estrogen Receptor antibody (ab53572)参考文献

ab53572 has not yet been referenced specifically in any publications.

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