概述

  • 产品名称Anti-ESRP2抗体
    参阅全部 ESRP2 一抗
  • 描述
    兔多克隆抗体to ESRP2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 36-85 (ATAGALGRDL GSDETDLILL VWQVVEPRSR QVGTLHKSLV RAEAAALSTQ) of Human ESRP2 (NP_079215).

  • 阳性对照
    • Hela cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab83034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/312500.

靶标

  • 功能mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
  • 组织特异性Epithelial cell-specific.
  • 序列相似性Belongs to the ESRP family.
    Contains 3 RRM (RNA recognition motif) domains.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epithelial splicing regulatory protein 2 antibody
    • ESRP 2 antibody
    • ESRP2 antibody
    • ESRP2_HUMAN antibody
    • FLJ21918 antibody
    • FLJ22248 antibody
    • RBM35B antibody
    • RNA binding motif protein 35A antibody
    • RNA binding motif protein 35B antibody
    • RNA binding protein 35B antibody
    • RNA-binding motif protein 35B antibody
    • RNA-binding protein 35B antibody
    see all

Anti-ESRP2 antibody 图像



  • Predicted band size : 78 kDa
    Western blot analysis of HepG2 cell lysate labeling ESRP2 with ab83034 at 1.0µg/ml.


  • Predicted band size : 78 kDa
    Western blot analysis of HeLa cell lysate labeling ESRP2 with ab83034 at 1.0µg/ml.
  • Anti-ESRP2 antibody (ab83034) at 1 µg/ml (in 5% skim milk / PBS buffer) + Hela cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 78 kDa
    Observed band size : 78 kDa
    Gel concentration: 12%

Anti-ESRP2 antibody (ab83034)参考文献

ab83034 has not yet been referenced specifically in any publications.

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