Anti-ESM1抗体(ab103590)
Key features and details
- Rabbit polyclonal to ESM1
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-ESM1抗体
参阅全部 ESM1 一抗 -
描述
兔多克隆抗体to ESM1 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant full length protein within Human ESM1 aa 1-200. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab103590于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 20 kDa.
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ICC/IF | (2) |
Use at an assay dependent concentration.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 20 kDa. |
ICC/IF
Use at an assay dependent concentration. |
靶标
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功能
May have potent implications in lung endothelial cell-leukocyte interactions. -
组织特异性
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. -
序列相似性
Contains 1 IGFBP N-terminal domain. -
翻译后修饰
May contain intrachain disulfide bonds. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 11082 Human
- Entrez Gene: 71690 Mouse
- Omim: 601521 Human
- SwissProt: Q9NQ30 Human
- SwissProt: Q9QYY7 Mouse
- Unigene: 129944 Human
- Unigene: 38929 Mouse
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别名
- Endocan antibody
- Endothelial cell specific molecule 1 antibody
- Endothelial cell-specific molecule 1 antibody
see all
图片
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Anti-ESM1 antibody (ab103590) at 1/500 dilution + Human kidney tissue lysate at 50 µg
Predicted band size: 20 kDa -
All lanes : Anti-ESM1 antibody (ab103590) at 1/500 dilution
Lane 1 : ESM1 transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 20 kDa
实验方案
数据表及文件
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Datasheet download
文献 (14)
ab103590 被引用在 14 文献中.
- Li YK et al. Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance. Int J Biol Sci 19:258-280 (2023). PubMed: 36594088
- Gu X et al. ESM1/HIF‑1α pathway modulates chronic intermittent hypoxia‑induced non‑small‑cell lung cancer proliferation, stemness and epithelial‑mesenchymal transition. Oncol Rep 45:1226-1234 (2021). PubMed: 33650648
- Choi HS et al. Anticancer Effect of Benzimidazole Derivatives, Especially Mebendazole, on Triple-Negative Breast Cancer (TNBC) and Radiotherapy-Resistant TNBC In Vivo and In Vitro. Molecules 26:N/A (2021). PubMed: 34500557
- Jin H & Kim HJ NK Cells Lose Their Cytotoxicity Function against Cancer Stem Cell-Rich Radiotherapy-Resistant Breast Cancer Cell Populations. Int J Mol Sci 22:N/A (2021). PubMed: 34502547
- Suzuki K et al. Recombinant Thrombomodulin Protects Against Lipopolysaccharide-induced Acute Respiratory Distress Syndrome Via Preservation of Pulmonary Endothelial Glycocalyx. Br J Pharmacol N/A:N/A (2020). PubMed: 32497259