Anti-eRF3B/GSPT2抗体(ab84180)

概述

  • 产品名称Anti-eRF3B/GSPT2抗体
    参阅全部 eRF3B/GSPT2 一抗
  • 描述
    兔多克隆抗体to eRF3B/GSPT2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 143-192 (MALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMMEEKEEIRKSKSV I) of Human eRF3B/GSPT2 (NP_060564)

  • 阳性对照
    • MCF7 cytoplasmic lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
  • 组织特异性Highly expressed in IUCC stage II colorectal cancer (CRC).
  • 序列相似性Belongs to the GTP-binding elongation factor family. ERF3 subfamily.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • eRF3b antibody
    • ERF3B_HUMAN antibody
    • Eukaryotic peptide chain release factor GTP-binding subunit ERF3B antibody
    • Eukaryotic peptide chain release factor subunit 3b antibody
    • G1 to S phase transition 2 antibody
    • G1 to S phase transition protein 2 homolog antibody
    • Gspt2 antibody
    • GST2 antibody
    • peptide chain release factor 3 antibody
    see all

Anti-eRF3B/GSPT2 antibody 图像

  • Anti-eRF3B/GSPT2 antibody (ab84180) at 1 µg/ml + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 69 kDa
    Observed band size : 69 kDa

Anti-eRF3B/GSPT2 antibody (ab84180)参考文献

ab84180 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab84180.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"