概述

  • 产品名称Anti-ERF抗体
    参阅全部 ERF 一抗
  • 描述
    兔多克隆抗体to ERF
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residue 498 and 548 of human ERF (NP_006485.2).

  • 阳性对照
    • Human controls: Anaplastic Thyroid Carcinoma, Breast Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Prostate Carcinoma Mouse Controls: Renal Cell Carcinoma, Teratoma

性能

应用

Our Abpromise guarantee covers the use of ab84773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation.
    • 组织特异性Highest levels in testis, ovary, pancreas, and heart.
    • 序列相似性Belongs to the ETS family.
      Contains 1 ETS DNA-binding domain.
    • 翻译后修饰Phosphorylated by multiple kinases including MAPK1/ERK2 at THR-526. Phosphorylation regulates the activity of ERF.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ERF antibody
      • ERF_HUMAN antibody
      • ETS domain containing transcription factor ERF antibody
      • ETS domain-containing transcription factor ERF antibody
      • Ets2 repressor factor antibody
      • PE 2 antibody
      • PE-2 antibody
      • PE2 antibody
      see all

    Anti-ERF antibody 图像

    • Staining of ERF by Immunohistochemistry on a formalin fixed, paraffin embedded section of human ovarian tumor using a 1/100 dilution of ab84773. Detection: DAB staining
    • Staining of ERF by Immunohistochemistry on a formalin fixed, paraffin embedded section of mouse teratoma using a 1/500 dilution of ab84773. Detection: DAB staining

    Anti-ERF antibody (ab84773)参考文献

    ab84773 has not yet been referenced specifically in any publications.

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