Anti-EREG抗体[MM0265- 12Y4] (ab89291)

概述

  • 产品名称
    Anti-EREG抗体[MM0265- 12Y4]
    参阅全部 EREG 一抗
  • 描述
    小鼠单克隆抗体[MM0265- 12Y4] to EREG
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Human EREG protein.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography.
  • 克隆
    单克隆
  • 克隆编号
    MM0265- 12Y4
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 19 kDa.

靶标

  • 功能
    May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.
  • 组织特异性
    In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.
  • 序列相似性
    Contains 1 EGF-like domain.
  • 细胞定位
    Cell membrane and Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epiregulin antibody
    • EPR antibody
    • ER antibody
    • Ereg antibody
    • EREG_HUMAN antibody
    • Proepiregulin antibody
    see all

实验方案

Anti-EREG antibody [MM0265- 12Y4] (ab89291)参考文献

This product has been referenced in:
  • Oliveras-Ferraros C  et al. Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells. Br J Cancer 106:1406-14 (2012). Read more (PubMed: 22491422) »

See 1 Publication for this product

Product Wall

Thank you for your reply. If the white band you are seeing on the darker background is at a molecular weight of 19 kDa, then it is the specific band of interest. The band can show up lighter than the background when the signal is too strong and the ECL...

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Thank you for contacting us. I am sorry this antibody is not giving good results in WB. Can you please provide some additional details of your experiment?

1) What type of samples were you testing and how were they prepared (lysis buffer, prot...

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Thank you for contacting us and your interest in our products. We have several antibodies directed against amphiregulin and epiregulin, however, as discussed over the phone, none have as yet been tested in IHC.

This does not mean that they wo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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