Anti-ERCC1抗体[SPM243], prediluted (ab54240)

概述

  • 产品名称Anti-ERCC1抗体[SPM243], prediluted
    参阅全部 ERCC1 一抗
  • 描述
    小鼠单克隆抗体[SPM243] to ERCC1, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat
  • 免疫原

    Recombinant full length protein (Human)

  • 阳性对照
    • A431 or HeLa cells, or tonsil tissue.

性能

应用

Our Abpromise guarantee covers the use of ab54240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready-to-use, for 30 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.
    • 疾病相关Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4) [MIM:610758]. COFS is a degenerative autosomal recessive disorder of prenatal onset affecting the brain, eye and spinal cord. After birth, it leads to brain atrophy, hypoplasia of the corpus callosum, hypotonia, cataracts, microcornea, optic atrophy, progressive joint contractures and growth failure. Facial dysmorphism is a constant feature. Abnormalities of the skull, eyes, limbs, heart and kidney also occur.
    • 序列相似性Belongs to the ERCC1/RAD10/SWI10 family.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • COFS 4 antibody
      • COFS4 antibody
      • DNA excision repair protein ERCC 1 antibody
      • DNA excision repair protein ERCC-1 antibody
      • DNA excision repair protein ERCC1 antibody
      • ERCC 1 antibody
      • ERCC1 antibody
      • ERCC1_HUMAN antibody
      • Excision repair cross complementation group 1 antibody
      • Excision repair cross complementing 1 antibody
      • Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody
      • Excision repair protein antibody
      • RAD 10 antibody
      • RAD10 antibody
      • UV 20 antibody
      • UV20 antibody
      see all

    Anti-ERCC1 antibody [SPM243], prediluted 图像

    • Ab54240 staining human ERCC1 in human tonsil tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    Anti-ERCC1 antibody [SPM243], prediluted (ab54240)参考文献

    ab54240 has not yet been referenced specifically in any publications.

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