Anti-ERCC1抗体[2326C1a] (ab66494)

概述

  • 产品名称
    Anti-ERCC1抗体[2326C1a]
    参阅全部 ERCC1 一抗
  • 描述
    小鼠单克隆抗体[2326C1a] to ERCC1
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment from a region of human ERCC1

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (~95%) fetal bovine serum.
  • 克隆
    单克隆
  • 克隆编号
    2326C1a
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab66494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Detects a band of approximately 34 kDa (predicted molecular weight: 32 kDa).
Dot blot Use at an assay dependent dilution.

靶标

  • 功能
    Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.
  • 疾病相关
    Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4) [MIM:610758]. COFS is a degenerative autosomal recessive disorder of prenatal onset affecting the brain, eye and spinal cord. After birth, it leads to brain atrophy, hypoplasia of the corpus callosum, hypotonia, cataracts, microcornea, optic atrophy, progressive joint contractures and growth failure. Facial dysmorphism is a constant feature. Abnormalities of the skull, eyes, limbs, heart and kidney also occur.
  • 序列相似性
    Belongs to the ERCC1/RAD10/SWI10 family.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • COFS 4 antibody
    • COFS4 antibody
    • DNA excision repair protein ERCC 1 antibody
    • DNA excision repair protein ERCC-1 antibody
    • DNA excision repair protein ERCC1 antibody
    • ERCC 1 antibody
    • ERCC1 antibody
    • ERCC1_HUMAN antibody
    • Excision repair cross complementation group 1 antibody
    • Excision repair cross complementing 1 antibody
    • Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody
    • Excision repair protein antibody
    • RAD 10 antibody
    • RAD10 antibody
    • UV 20 antibody
    • UV20 antibody
    see all

Anti-ERCC1 antibody [2326C1a] 图像

实验方案

Anti-ERCC1 antibody [2326C1a] (ab66494)参考文献

ab66494 has not yet been referenced specifically in any publications.

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