概述

  • 产品名称
    Anti-Epsin 2抗体
    参阅全部 Epsin 2 一抗
  • 描述
    兔多克隆抗体to Epsin 2
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal sequence of human Epsin 2.

  • 阳性对照
    • Extracts from HepG2 cells or HUVEC cells.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab74942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 68 kDa.
ELISA 1/20000.

靶标

  • 功能
    Plays a role in the formation of clathrin-coated invaginations and endocytosis.
  • 组织特异性
    Highest expression is found in brain. Detected at lower levels in lung and liver.
  • 序列相似性
    Belongs to the epsin family.
    Contains 1 ENTH (epsin N-terminal homology) domain.
    Contains 2 UIM (ubiquitin-interacting motif) repeats.
  • 结构域
    The NPF repeat domain is involved in EPS15 binding.
    The DPW repeat domain is involved in AP-2 and clathrin binding.
  • 翻译后修饰
    Ubiquitinated.
  • 细胞定位
    Cytoplasm. Cytoplasmic vesicle > clathrin-coated vesicle. In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EHB21 antibody
    • EPN 2 antibody
    • Epn2 antibody
    • EPN2_HUMAN antibody
    • EPS 15 interacting protein 2 antibody
    • EPS-15-interacting protein 2 antibody
    • Eps15 binding protein antibody
    • Epsin 2 antibody
    • Epsin-2 antibody
    • Epsin2 antibody
    • KIAA1065 antibody
    • OTTHUMP00000065808 antibody
    • OTTHUMP00000065809 antibody
    • OTTHUMP00000065810 antibody
    • OTTHUMP00000065811 antibody
    • OTTHUMP00000065889 antibody
    see all

图片

  • All lanes : Anti-Epsin 2 antibody (ab74942) at 1/500 dilution

    Lane 1 : Extracts from HepG2 cells
    Lane 2 : Extracts from HUVEC cells
    Lane 3 : Extracts from HepG2 cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 68 kDa
    Observed band size : 68 kDa
    Additional bands at : 85 kDa. We are unsure as to the identity of these extra bands.

实验方案

文献

ab74942 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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