RabMAb

Anti-EPS8抗体[EPR6112] (ab124882)

概述

  • 产品名称Anti-EPS8抗体[EPR6112]
    参阅全部 EPS8 一抗
  • 描述
    兔单克隆抗体[EPR6112] to EPS8
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
    不适用于: Flow Cyt or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues near the N-terminus of Human EPS8.

  • 阳性对照
    • HeLa, A375, 293T, and K562 cell lysates, Human kidney tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab124882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 97 kDa (predicted molecular weight: 92 kDa).
IHC-P 1/100 - 1/250. antigen retrieval is recommended.
ICC/IF 1/50 - 1/100.
  • 应用说明Is unsuitable for Flow Cyt or IP.
  • 靶标

    • 功能Upon binding to EGF receptor enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.
    • 组织特异性Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells.
    • 序列相似性Belongs to the EPS8 family.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • 结构域The SH3 domain mediates interaction with SHB.
    • 翻译后修饰Phosphorylated by several receptor tyrosine kinases.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Epidermal growth factor receptor kinase substrate 8 antibody
      • Epidermal growth factor receptor pathway substrate 8 antibody
      • EPS 8 antibody
      • EPS8 antibody
      • EPS8_HUMAN antibody
      see all

    Anti-EPS8 antibody [EPR6112] 图像

    • All lanes : Anti-EPS8 antibody [EPR6112] (ab124882) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : A375 cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 92 kDa
    • Staining of EPS8 in Paraffin-embedded Human kidney tissue by Immunohistochemistry using ab124882 at a dilution of 1/100.

    Anti-EPS8 antibody [EPR6112] (ab124882)参考文献

    ab124882 has not yet been referenced specifically in any publications.

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