概述

  • 产品名称Anti-EPS8抗体
    参阅全部 EPS8 一抗
  • 描述
    兔多克隆抗体to EPS8
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 761- 822 (DELRTVCPEG ARVYSQITVQ KAALEDSSGS SELQEIMRRR QEKISAAASD SGVESFDEGS SH) of Human EPS8 (NP_004438).

  • 阳性对照
    • WB: H1299, HeLa cell lysates IHC-P: Gastric CA

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 1% BSA, 1X PBS, pH 7
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified by antigen affinity chromatography.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96144 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 92 kDa.
IHC-P 1/100 - 1/250.

靶标

  • 功能Upon binding to EGF receptor enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.
  • 组织特异性Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells.
  • 序列相似性Belongs to the EPS8 family.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • 结构域The SH3 domain mediates interaction with SHB.
  • 翻译后修饰Phosphorylated by several receptor tyrosine kinases.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epidermal growth factor receptor kinase substrate 8 antibody
    • Epidermal growth factor receptor pathway substrate 8 antibody
    • EPS 8 antibody
    • EPS8 antibody
    • EPS8_HUMAN antibody
    see all

Anti-EPS8 antibody 图像

  • All lanes : Anti-EPS8 antibody (ab96144) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : Hela whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 92 kDa
  • ab96144, at 1/100 dilution, staining EPS8 in paraffin embedded Gastric CA by Immunohistochemical analysis.

Anti-EPS8 antibody (ab96144)参考文献

ab96144 has not yet been referenced specifically in any publications.

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